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New Cancer Prevention Findings from E. Sacco and…

New Cancer Prevention Findings from E. Sacco and Co-Authors Described (Natural Compounds in Cancer Prevention: Effects of Coffee Extracts and Their…

Oncology – Cancer Prevention

(Cancer Weekly)

New Cancer Prevention Findings from E. Sacco and Co-Authors Described (Natural Compounds in Cancer Prevention: Effects of Coffee Extracts and Their Main Polyphenolic Component, 5-O-Caffeoylquinic Acid, on Oncogenic Ras Proteins)

By a News Reporter-Staff News Editor at Cancer Weekly — Researchers detail new data in Oncology – Cancer Prevention. According to news reporting originating from Milan, Italy, by NewsRx correspondents, research stated, “Recent epidemiological studies have demonstrated that the consumption of healthy foods that are particularly rich in polyphenols might reduce the incidence of cancer and neurodegenerative diseases. In particular, chlorogenic acids (CGAs) occur ubiquitously in food and represent the most abundant polyphenols in the human diet.”

Our news editors obtained a quote from the research, “A number of beneficial biological effects of CGAs, such as anti-inflammatory activity, anti-carcinogenic activity, and protection against neurodegenerative diseases, have been reported. However, the molecular mechanisms at the base of these biological activities have not yet been investigated in depth.”

According to the news editors, the research concluded: “By combining NMR spectroscopy, molecular docking, surface plasmon resonance and ex vivo assays of the Ras-dependent breast cancer cell line MDA-MB-231, we contribute to the elucidation of the molecular basis of the activity of CGAs and natural extracts from green and roasted coffee beans as chemoprotective dietary supplements.”

For more information on this research see: Natural Compounds in Cancer Prevention: Effects of Coffee Extracts and Their Main Polyphenolic Component, 5-O-Caffeoylquinic Acid, on Oncogenic Ras Proteins. Chemistry-An Asian Journal, 2017;12(18):2457-2466. Chemistry-An Asian Journal can be contacted at: Wiley-V C H Verlag Gmbh, Postfach 101161, 69451 Weinheim, Germany (see also Oncology – Cancer Prevention).

The news editors report that additional information may be obtained by contacting E. Sacco, SysBio Center Syst Biol, I-20126 Milan, Italy. Additional authors for this research include C. Ciaramelli, R. Tisi, M. Spinelli, G. De Sanctis, A. Palmioli and C. Airoldi.

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